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Vitamin D levels and body antioxidant status in ischemic stroke patients: A case-control study
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Neurological Disorders

ISSN: 2329-6895

Open Access

Vitamin D levels and body antioxidant status in ischemic stroke patients: A case-control study


7th International Conference on Brain Injury & Neurological Disorders

April 10-12, 2018 | Amsterdam, Netherlands

Reza Amani, Laleh Afshari and Farhad Soltani

Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Dept. of Nutrition, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Anesthesiology, ICU, Golestan Medical Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Scientific Tracks Abstracts: J Neurol Disord

Abstract :

Background: Stroke is the second cause of death among elderly people and oxidative stress plays important role in brain damage after stroke. The aim of this study was to evaluate the status of Vitamin D, antioxidant enzymes, and the relation between the ischemic stroke patients. Materials and Methods: This case�control study was carried out on 36 patients with ischemic stroke patients and 36 matched subjects as controls. Intake of fruits and vegetables, exposure of sunlight, serum lipid profile, concentrations of serum Vitamin D, activities of serum superoxide dismutase, and glutathione peroxidase enzymes were determined. Results: Severe Vitamin D deficiency was seen in 30% of the patients versus 11% of the controls (P < 0.05). Consumption of fruits and vegetables was lower in patients than that of controls (P < 0.05). Activities of antioxidant enzymes and intake of fruits were positively correlated in stroke patients (P = 0.02). The most potent predictors of stroke risk were hypertension, high levels of low-density lipoprotein cholesterol (LDL-C) and history of cardiovascular disease (CVD) (odds ratios: 3.33, 3.15, and 3.14, respectively, P < 0.05 for all). There was no association between 25(OH) D levels with activities of serum antioxidant enzymes and lipid profile in the two groups. Conclusion: Ischemic stroke patients have higher prevalence of severe vitamin D deficiency and lower intakes of fruits and vegetables. High levels of blood pressure, history of CVD, and high LDL-C levels are the strongest predictors of ischemic stroke.

Biography :

Professor Reza Amani is academic member at Isfahan University of Medical Sciences (IUMS), Isfahan, Iran. He received his PhD and MSc in Nutrition Science from Tabriz University of Medical Sciences, Tabriz, Iran. He has obtained his fellowship in Clinical Nutrition. He has also worked at the University of Sydney, Australia as visiting scholar. Dr Amani has published more than 120 scientific papers in Persian and English academic journals and has supervised above 50 post graduate theses and research projects. Currently, he is working as the Head of Food Security Research Center at IUMS. He has been awarded as eminent researcher at Ahvaz Jundishapur University of Medical Sciences for five years.
Email:rezaamani@hotmail.com
 

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