Vitamin D synergies with disease modifying therapies for multiple sclerosis

International Congress on Neuroimmunology and Therapeutics

DoubleTree by Hilton Hotel San Francisco Airport, San Francisco, CA, USA

Bijal Mehta

Posters-Accepted Abstracts: J Neurol Disord

Abstract :

Disease Modifying Therapies (DMT) for Multiple Sclerosis have seen a relative explosion from a few treatments a decade ago to over a dozen currently. Vitamin D and an association with Multiple Sclerosis (MS) continue to be demonstrated in the research literature. However, as correction of patientâ??s serum vitamin D levels is occurring in MS clinics world-wide, little data has emerged as to how normal vitamin D levels effects patients on various disease modifying therapies. This presentation will discuss the mechanisms of action of vitamin D on the neuro-immune system, along with the effects of current and future disease modifying therapies. Potential and proven synergies will be discussed from the literature. A discussion of the potential variances between the animal models used to test vitamin D and DMTs with human clinical trials will be discussed. Lastly, a list of other potential synergistic compounds that have yet to be tested in clinical trials will be reviewed.