Molecular Biology: Open Access

Dr. Mohamed Al-Agamy

Dr. Mohamed Al-Agamy
Associate Professor of Microbiology, College of Pharmacy, Riyadh
King Saud University
Saudi Arabia

Biography

1. Al-Agamy, M.H., Hefny, H.M., Fouda, S.I., Mansy, M.S.M. and Ashour, M.S.E.: Studies on microbial urinary tract infections in diabetic patients. Az. J. Microbiol. Vol. 44, April, 1999; 107-121. 2. Wiegand, I., Noha, K., Al-Agamy, M.H. and Wiedeman, B.: First detection of transferable quinolone resistance determinant in clinical Providencia stuartti strains in Egypt. Clin Microbiol Infect. Vol. 10: (supl 3) 64: 2004. 3. Al-Agamy, M.H., Ashour, M.S.E. and Wiegand, I.: First description of CTX-M genes from Egyptian Escherichia coli strains. International Journal of antimicrobial Agents, Vol. 27: 2006; 545-548. 4. Al-Agamy, M.H., Wiegand, I., Wiedemann, B., Ashour, M.S.E, Helal, A-S.A-H. and El-Ghareeb. Characterization of molecular resistance mechanisms to chloramphenicol in extended spectrum β-lactamase-producing Escherichia coli strains. N. Egypt. J. Microbiol. Vol. 14, September, 2006; 233-246. 5. Al-Agamy, M.H.: Detection of chloramphenicol resistance genes in broad spectrum β lactamase-producing Escherichia coli strains. N. Egypt. J. Microbiol. Vol. 13: January, 2006; 17-28. 6. Al-Agamy, M.H., I. Wiegand., B. Wiedemann, M.S.E. Ashour, A-S.A-H. Helal and K. A. El-Ghareeb, K. A.: Detection of mutations in gyrA and parC genes in quinolone-resistant clinical isolates of Escherichia coli. N. Egypt. J. Microbiol. Vol. 18: September, 2007; 98-108. 7. Ashour, M.S., El-Loboudy, S.S. Al-Agamy, M.H. and Mahmoud, M.A.: Production and properties of an extra-cellular protease from Bacillus species. N. Egypt. J. Microbiol. Vol. 18: September, 2007; 267-284. 8. Al-Agamy, M.H., Ali, M.S., Salem, M.M. and Mohamed, T.R:. Faecal colonization by extended-spectrum beta-lactamase-producing Escherichia coli from hospitalized patients. N. Egypt. J. Microbiol. Vol. 19: January, 2008; 285-314. 9. Mahmoud, M. A., Al-Agamy, M.H., El-Loboudy, S. S., and Ashour, M. S.: Purification and characterization of neutral protease from Bacillus subtilis strain. N. Egypt. J. Microbiol. Vol.22: January, 2009; 131-143. 10. Al-Agamy, M.H.: Pseudomonas aeruginosa clinical isolates producing metallo-B-lactamases VIM in Saudi Arabia. Egypt. J. Biomed. Sci. Vol. 29: March, 2009; 185-195. 11. Al-Agamy, M.H., Tawfic, A-K.F., and Shibl, A.M.: Prevalence and characterization of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Saudi Arabia. Egypt. J. Biomed. Sci. Vol. 29: March, 2009; 202-211. 12. Al-Agamy, M.H., Tawfic, A-K.F., Radwan, H.H. and Shibl, A.M.: High prevalence of metallo-beta-lactamases in Pseudomonas aeruginosa from Riyadh, Saudi Arabia. Journal of Chemotherapy, Vol. 21(4): August, 2009; 461-462. 13. Al-Agamy, M.H., Tawfic, A-K.F. and Shibl, A.M.: Prevalence and molecular characterization of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in Riyadh, Saudi Arabia. Annals of Saudi Medicine, Vol. 29(4) July-August, 2009; 253-257. 14. Al-Agamy, M.H., Shibl, A.M. Tawfic, A-K.F. and Elbannai, A. R.: Klebsiella pneumoniae producing CTX-M-15 from neonatal intensive care unit in Saudi Arabia. Research Journal of Microbiology, 4(7): 2009; 278-285. 15. Al-Agamy, M.H..: Review; Tools of Biological Warfare. Research Journal of Microbiology, 6(3): 2011; 193-245. 16. Tawfik A.F., Alswailem A.M. Shibl A.M., Al-Agamy, M.H..: Prevalence and genetic characteristics of TEM, SHV, and CTX-M in clinical Klebsiella pneumoniae isolates from Saudi Arabia. Microbial Drug Resist. 2011, 17(3):383-388. 17. Abdel-Aziz, A.A., Asiri, Y.A. and Al-Agamy, M.H.: Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study. Eur J Med Chem. 2011. 46(11):5487-97. 18. Al-Agamy, M.H.: Antimicrobial resistance patterns and molecular characterizations of tetracycline, streptomycin, sulphonamide and chloramphenicol resistances in uropathogenic Escherichia coli strains. Accepted in Journal of Infection in Developing Countries (September, 2011). 19. Al-Agamy, M.H., Shibl, A.M. and Tawfic, A-K.F.: Antimicrobial resistance pattern and prevalence of metallo-β-lactamases in Pseudomonas aeruginosa from Saudi Arabia. Accepted in African Journal of Microbiology Research (October, 2011). 20. Al-Agamy, M.H., Shibl, A.M.: Mechanisms of Fluoroquinolone Resistance in Escherichia coli Isolates from Saudi Arabia. Accepted in African Journal of Biotechnology (November, 2011). 21. Al-Agamy, M.H.: Genetic basis of cefotaxime resistant isolates of Klebsiella pneumoniae from Cairo. Accepted in African Journal of Microbiology Research (November, 2011). 22. Tawfic, A-K.F., Atef M. Shibl, A.M., Aljohi, M.A., Altammami, M.A. and Al-Agamy, M.H.: Distribution of Ambler class A, B and D β-lactamases among Pseudomonas aeruginosa isolates in Saudi Arabia. Accepted in Burns (November, 2011).

Research Interest

The major components of my research interests are: 1. Characterization of the .resistance mechanisms of Enterobacteriaceae to antibiotics 2. Screening of extended spectrum β-lactamase (ESBL), metallo-β-lactamase (MBL), and AmpC plasmid mediated β-lactamases in Enterobacteriaceae and Pseudomonas. 3. Phenotypic and genotypic characterization of ESBL, MBL and AmpC. 4. Genetic basis of resistance mechanisms in Enterobacteriaceae, Pseudomonas and Acinetobacter species. 5. Analysis and prevalence of plasmid mediated quinolone resistance such as qnr, aac(6)-Ib-cr, qepA genes. 6. Role of mobile genetic elements that enhance mobilization of the resistance genes. 7. Investigation of methicillin resistant Staphylococcus aureus (MRSA).