Resistant Hypertension

Resistant hypertension is defined as blood pressure that remains above goal in spite of concurrent use of three antihypertensive agents of different classes, one of which is a diuretic. Resistant hypertension is most often due to insufficient medical therapy.The prognosis of resistant hypertension is unknown, but cardiovascular risk is undoubtedly increased as patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors such as obesity, sleep apnea, diabetes, and chronic kidney disease.