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Effect of Alternative Medicine and Pharmacoeconomics |
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Open Access

Effect of Alternative Medicine and Pharmacoeconomics

Special Issue Article

Pages: 1 - 1

Eficacy of fibromyalgia treatment using Bach Flower Therapy: Preliminary results

Jozélio Freire de Carvalho,1,2* Cassia Jesus Rocha,2 Natasha Lima Bastos de Queiroz2, Jordan Campos2

Statement of the problem: Fibromyalgia (FM) is a prevalent disease and often presents symptoms of anxiety and depression. Bach florals (BF) are widely used to treat such manifestations. No studies on the use of BF in FM were found.
Objective: To evaluate the effects of BF (Rescue) in FM patients.
Patients and methods: 6 patients and 6 healthy controls were included. They were evaluated at pre-intervention and after 60 days of BF using. Demographic data, anxiety and depression were evaluated by Beck inventories; sleep quality by the Pittsburgh scale and symptoms of dysbiosis by symptoms form.
Results: The median age was 60 years old (22-77) in patients and 41 (40-43) years old in controls. The disease duration was 3 years (4 months -10 years old). Caucasian race was 33% in the patient group and 66% in the controls. There was a statistically significant reduction between the Beck Anxiety Questionnaire before and after 60 days [16 (6-42) vs. 10 (2-27), p=0.05), Beck Depression Questionnaire before and after 60 days [16 (8-52) vs. 10 (6-35), p=0.02) and dysbiosis questionnaire before and after 60 days [18 (10-27) vs. 15 .5 (7-27), p=0.03). Regarding the sleep form, no significant differences were observed before and after BF.
Conclusion and significance: Treatment with Bach flower in patients with fibromyalgia seems promising, as it reduces tender points, symptoms of depression and anxiety, as well as improvement of symptoms of dysbiosis.

Special Issue Article

Pages: 2 - 2

A single case study on Atopic Eczematous Dermatitis with special reference to Vicharchika

Anjana L.Siddapur

“Kushnaati vapuh iti kustah” that which disfigures or deforms a person’s physique is Kusta. One such common type of Kusta which is commonly encountered by Ayurveda physicians in day today practice is Vicharchika, which is characterized by Pidaka (vesicles), Srava (oozing), Shyava varna (discolouration) and Kandu (itching). Susruta samhita also gives a reference of ruksha Vicharchika which is also seen in clinical practice. Treatment in contemporary science restricts to the hindrance of the complaints but not from the route and condition is seen to reappear inspite of repeated management using antihistamines and topical steroid applications. A patient presented with clinical features vesicles, erythematous skin lesions and discharge with intense itching at the posterior part of lower limbs, forearms, front and back of chest, abdomen & inguinal region. He was treated with Virechana and Agada formulations, considering the history. Dooshivisha in the samprapti of that condition. Results were encouraging and remarkable.

Special Issue Article

Pages: 3 - 4

Phenolic characterization and biological potential of Pterospartum tridentatum phenolic-rich extracts

Ana C. Gonçalves,1* Ana R. Nunes,1 Manuel Simões 2, Gilberto Alves 1, Luís R. Silva 1

For a long time, fruits, vegetables and natural plants have been a target of many studies and their consumption has been increasingly encouraged owing to their nutritional value and abundance of nutritional and bioactive compounds, known for their protective effects. Among plants, and although Pterospartum tridentatum, an endemic plant from the northwest of the Iberian Peninsula and Morocco, is largely used in culinary, their phytochemical profile and therapeutic effects remain little known. Therefore, we decided to determine the phenolic composition of infusions and hydroethanolic extracts of P. tridentatum by high-performance liquid chromatography method coupled to a diode array detector analysis. Furthermore, we also evaluated their biological potential, namely antioxidative and antiproliferative effects, and capacity to inhibit α-glucosidase activity. In total, 13 phenolics were found; genistein was the major one, comprising 36.8 and 20.2% of total phenolics in infusion and hydroethanolic extracts, respectively. Regarding the biological potential, the hydroethanolic extract was the most active against 2,2- diphenyl-1-picrylhydrazylâ? and in inhibiting α-glucosidase activity. On the other hand, the infusion proved to be a remarkable free radical scavenger against superoxide and nitric oxide free radical species, and in protecting human erythrocytes facing peroxyl radicals. Both extracts also showed cytotoxic selectivity for human epithelial colorectal adenocarcinoma (Caco-2) cells when compared to the NHDF normal cell line, inhibiting its growth in a dose-dependent manner. Furthermore, they also showed protective effects against oxidative stress induced by tert-butyl hydroperoxide on these cancer cells. Overall, the obtained data suggest that these extracts may be interesting to enrich nutraceutical, dietary and food supplements, and pharmaceutical drugs; however, more studies are needed to unravel ensure safe dosage of both extracts and to incite their use in new formulations, functional foods, pharmaceutical preparations and/or food additives.

Special Issue Article

Pages: 5 - 5

Management of recurrent urethral stricture by Uttar Basti: A case study

Alok Kumar

Urethral stricture is the very common problem occurred in the patients after prolonged urinary tract infection, urethral injury or post-surgical intervention performed through per urethral. In Ayurvedic literature urethral stricture may be correlated as mutrotsanga mentioned in Sushruta Samhita. One of the prime literature in Ayurvedic surgery. Now day as the science advances with technology various surgeries like urethrolithotomy, Trans urethral removal of prostate (TURP), cystoscopy are performed with telescopic instruments like cystoscope. During these procedure the urethral lining of mucosa get injured and later on develop the scary fibrosis that lead the urethral stricture in the urethra. The most common way to overcome this problem is surgery i.e. urethroplasty. But the recurrence rate is good enough to think the alternative. In Ayurvedic literature uttarbasti is the procedure in which some medicinal preparation are introduced per urethral. In this particular case study we use the apamarga kshara tail oil for the uttarbasti procedure in the patient having history of recurrent urethral stricture. Patient also underwent urethroplasty twice. The results found in the case are encouraging enough. The study was completed in North eastern Institute of Ayurveda And Homoeopathy, Ayurveda hospital Shillong.

Special Issue Article

Pages: 6 - 7

Polycystic Ovarian Syndrome: The mother of all lifestyle disorders in women - An Ayurvedic approach to its management

Monika Chauhan

PCOS is probably fastest growing health hazard amongst women of reproductive age. The prevalence of this disease in general population is about 5-10% world-wide. This familial disorder appears to be inherited as a complex genetic trait.The association of amenorrhoea with bilateral polycystic ovaries and obesity was first described by Stein & Leventhal. It is characterized by a combination of hyperandrogenism (clinical or biochemical), chronic anovulation and polycystic ovaries. This is frequently associated with insulin resistance and obesity. This condition is receiving so much attention due to its high prevalence and possible reproductive, metabolic, and cardiovascular consequences. It is the most common cause of hyperandrogenism, hirsutism, and anovulatory infertility in developed countries.As the aetiology is poorly understood, there is controversy about diagnostic criteria, clinical features of the syndrome. The management of PCOS is difficult and challenging task, faced by modern gynaecologists. So the holistic approach is demanded specially in Indian subcontinent because of high prevalence here (52%). This particular feminine disorder is not described word to word in Ayurveda. PCOS associated some features are closely related with some of Yonivyapada yet some features nearly bring into its relation with Aartvadushti. Word Aartava has been used extensively in Samhita in context of menstrual blood, ovum and ovarian hormones. Ayurveda, the age-old science of life, speaks of prevention and cure of PCOS through Aahar (Diet), Vihaar (Lifestyle Modification) and Aushadh (Medicine). Possible line of treatment is stipulated with Nidanaparivarjan, Samshodhana, Aaganeya Dravya, Savayonivardhana Dravya.

Value Added Abstracts

Pages: 9 - 9

Evaluate the efficacy of Darvyadi lauha(A herbo mineral compound) in the management of hepatocellular jaundice(Kamala) and hepato-protective activity in paracetamol induced hepatotoxicity- A randomised controlled clinical

Arshathjyothi P S

Statement Introduction: Liver diseases cause significant mortality and morbidity not only in Indian population but also in world. Due to the changing lifestyle the liver is affected even in early adolescence itself, so an excellent Yakrut uthejaka dravyas (hepato-protective drugs) are need of the hour. It was observed in some cases that the liver injury even with herbal preparations. 2017 world journal of hepatology had published Ayurveda drug induced liver injury. The title of the study is to ‘Evaluate the efficacy of Darvyadi lauha in the management of hepatocellular jaundice (Kamala) and hepatoprotective activity in paracetamol induced hepatotoxicity- a randomised controlled clinical.Methodology;A combination of experimental and clinical study. In primary study efficacy of Darvyadi lauha as a hepatoprotective drug explored in the paracetamol induced Wistar rats.30 rats were classified under five groups. After assessment liver parameters, antioxidant potential and hepatocyte structures found significant changes in Darvyadi lauha treated group. Clinical study conducted in hepato- cellular jaundice patients Results; Darvyadi lauha at 400mg/kg body weight have shown promising results hepatoprotective activity against Paracetamol induced hepatic damage. The drug is having significant antioxidant potential. 400mg/kg body weight drug group almost resolved paracetamol induced hepatic damage

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