Sex has a physical act that makes men more divine. Sex with education event less pain. Sex desire has increasing all sides of world, many land lady engage in sex outside marriage. A woman who sleeps with a man she just met signals that she has low self-esteem or that she is actually only using him for sex. The study, led by the University of Pune, found that more than half of young out land lady reported problems with extra maternal sexual affair function, with the probability of reporting sexual approach increasing over time. The study discovered that two years after their initial some land lady out diagnosis, nearly 53 percent of young adults 18 to 69 years old still reported some degree of affected common mistake in extra maternal affair and caught in sexting for sex.

As you aware, if temperature increases (Absence of fever)after 31 degree Celsius , Warm sensitive neurons increase their firing rate and inhibit Cold sensitive neurons as core temperature increases. As temperature drops, the firing rate of Warm sensitive neurons decreases, reducing their inhibition, and Cold sensitive neurons which respond by increasing their firing rates.On the contrary to increase of temperature, in fever the firing rate of Warm sensitive neurons decreases, the firing rate of Cold sensitive neurons increases as core temperature increases. inhibit warm sensitive neurons. The temperature increasing and decreasing controlled by the brain. The firing rate of Warm sensitive neurons and Cold sensitive neurons also controlled by the brain.

ketogenic diet (KD), the body utilizes energy obtained from free fatty acids (FFAs) released from It has been recently shown that nutritional ketosis is effective against seizure disorders and various acute/chronic neurological disorders. Physiologically, glucose is the primary metabolic fuel for cells. However, many neurodegenerative disorders have been associated with impaired glucose transport/metabolism and with mitochondrial dysfunction, such as Alzheimer’s/Parkinson’s disease, gene disorders, and traumatic brain injury. Ketone bodies and tricarboxylic acid cycle intermediates represent alternative fuels for the brain and can bypass the ratelimiting steps associated with impaired neuronal glucose metabolism. Therefore, therapeutic ketosis can be considered as a metabolic therapy by providing alternative energy substrates. It has been estimated that the brain derives over 60% of its total energy from ketones when glucose availability is limited. In fact, after prolonged peri fasting or adipose tissue. Because the brain is unable to derive significant energy from FFAs, hepatic ketogenesis converts FFAs into ketone bodies hydroxybutyrate (BHB) and acetoacetate (AcAc)-while a percentage of AcAc spontaneously decarboxylates to acetone. Large quantities of ketone bodies accumulate in the blood through this mechanism. This represents a state of normal physiological ketosis and can be therapeutic. Ketone bodies are transported across the blood-brain barrier by monocarboxylic ac transporters to fuel brain function. Starvation or nutritional ketosis is an essential survival mechanism that ensures metabolic flexibility during prolonged fasting or lack of carbohydrate ingestion. Therapeutic ketosis leads to metabolic adaptations that may improve brain metabolism, restore mitochondrial ATP production, decrease reactive oxygen species production, reduce inflammation, and increase neurotrophic factors’ function. It has been shown that KD mimics the effects of fasting and the lack of glucose/insulin signaling, promoting a metabolic shift towards fatty acid utilization. In this work, the author reports a number of successful case reports treated through metabolic ketosis

Much research has highlighted the aging process as a global, multi-faceted issue, focusing on modifiable factors that can improve physical health and psychosocial well-being in late life. This is particularly true for both developed and developing countries, which are likely to face long-term issues in health and psychosocial care as the aging of their population increases. This paper aims to review recent advances in our knowledge of middle and late-life well-being in order to better understand the role of well-being and spirituality/religiosity across adulthood. The results of the selected studies allow us to conclude that subjective well-being and religious practices are significant determinants shaping the overall psychological well-being, life satisfaction, and social functioning of the older population. Limitations and implications of the study will also be discussed

All treatments for fever are based on the belief that fits is the result of 41 degree Celsius temperature and it damages cells of brain and body. At the same time there is no evidence based tests or concrete diagnosing methods to the belief that fits and brain damage is the result of pyrexia [1]. Necessary ingredients to destroy brain cells and fits cannot be seen in fever.In pyrexia or absence of fever a fainted patient fell on the floor with unconscious state and destroy cells of brain, and necessary ingredients to become conscious are same. When disease increases essential blood circulation and energy level also decreases. The vertical height between heart and brain is more than one feet. When the disease becomes severe, ability to pump the blood to the brain decreases. As a result of this brain cells are damaged. so the patient might be paralyzed or may even die. In pyrexia or absence of fever, when blood flow to the brain decreases and fits are formed. There is no other way than this to increase blood circulation to the brain. It is a sensible and discreet action of brain to protect the life or organ.

Aimï¼?To explore the impact of the head nurse’s managerial competences (HNMC) on the occupational burn-out of staff. Background ï¼? Occupational burn-out was considered as an essential factor contributing to the staff’s leaving. However, little is known about the impact of HNMC on the occupational burn-out of staff. Methodï¼?A cross-sectional survey conducted in a teaching hospital in central Taiwan which has 603 nurses. Questionnaires inquiring perceived HNMC, personal burn-out (PBO) and work related burn-out (WBO) were filled out in a network form. Resultsï¼?The respondents included 25 head nurses and 484 nurses. It was observed that 7 and 2 out of the 9 dimensions of HNMC respectively were significantly correlated with PBO and WBO scores in mild burn-out group. Conclusionsï¼?HNMC did have impact on the occupational burnout of staffs in mild group, but not in moderate and severe ones.Implications for Nursing Management HNMC was essential for nurses in mild burn-out status. Crucial factors contribute to moderate and severe occupational burn-out requires would be the focus for further studies.

Traditional high fidelity patient simulation (HFPS) is a teaching and learning strategy that offers an effective learning environment for nursing students to develop their decision making and critical thinking skills. Simulation experiences have been used in nursing curricula as an alternative to clinical placement and to assist students in the preparation for care of the challenges of high acuity patients. Baccalaureate degree in nursing programs are designed to prepare a generalist nurse for entry to practice to practise safely, competently and ethically along the continuum of care in situations of health and illness throughout a client’s lifespan. However, although nursing programs have increased enrollment to meet the projected nursing shortage; specialty clinical sites for pediatric placements have been challenging to secure clinical sites for opportunities for students to achieve clinical objectives and skills needed to provide care in the partnership of family centred care of the pediatric client. The use of simulation as a strategy to fill the gap in pediatric learning opportunities and to complement pediatric clinical experiences are essential in nursing programs to meet the students’ learning needs

Background Pharmacology is one of the single most substantial parts of the National Council Licensure Examination-Registered Nurses (NCLEX-RN) exam (~19%) which is a standardized psychometric exam. Gamification is applying game elements in non-game settings to influence an individual’s behavior in doing something they would not have wanted to do otherwise by giving them a reason to Method The objective of this study is to study the effect of a student self-developed pharmacology game in a nursing pharmacology course to improve their depth of understanding of the subject. Results The majority of questions came from a third of the class who participated with multiple questions created. Students who worked over three hours of question writing and game participation correlated 0.66 with a higher passing grade on a national pharmacology benchmark testing exam. The younger student did play the game more often but did not write more questions than their older peers. Conclusion Students who participated in question writing and game participation had significantly higher scores than students' who did not participate in the question writing or game participation.

Poor and poorest can desire for sex. Open day meditation has the same effect on our brains as sex. 20 new normal orgasms in a research row and affordable in all color of skin. Orgasms can a sexual event, which has attained at the culmination of a sexual activity. However, not all orgasms have derived from sexual activity to extended act. There are other activities, beyond sex, that also give the same feeling as an orgasm. Meditation can accept surprised to note that meditation has the same effect on our brains as sex. In both cases, there is a rush of blood to the prefrontal area by side brain. Sex and meditation both lead us to a state of bliss and lack of self awareness. Sexual context become immune to our thoughts, desires, worries, pain and other worldly feelings. The only difference between a sexual orgasm and a meditation led one has that while the former gives us physical delight; the latter has spiritual in experience. Coregasms Orgasms can achieve by non-sexual and non-meditative activity performance smart co worker. First study in India found that 40 per cent of women experience orgasms during crunches and workout like planks. Twenty per cent of the women reported that they achieved orgasm at times when they were practicing yoga in front of male trainer. Some women reported experiencing sexual pleasure while horse riding, swimming and cycling. This probably has to do with blood rushing to the pelvic areas while doing these exercises. Delivering a child women have been reported to experience sexual pleasure during the childbirth process, childbirth process stimulates the same spots that would be activated during sexual intercourse. A lot of beta-endorphins, prolactin and oxytocin omega has released during delivery, which give the new mothers a sexual-orgasm like experience. Sleepgasms has 37 per cent women had orgasms in their sleep. It has conjectured that there may be an increased flow of blood in the pelvic area during the REM of the eye when women are asleep. This phenomenon, when combined with brain being shut down, can result in an orgasm

Intracerebral hemorrhage(ICH), the main subtype of stroke has the characteristics of acute onset, poor prognosis and high mortality. Early mobilization can reduce the incidence of complications in patients with ICH, improve their physiological functions and quality of life, and reduce health care costs. This review summarized and analyzed the related researches on early mobilization of ICH patients from several aspects (time to initiation, mobilization content, influencing factors and the effects of mobilization) to provide references for related researches and clinical practice. Methods: Literature review.Results: Based on the characteristics of ICH, moving too early may cause patients’ blood pressure fluctuations, increasing the risk of rebleeding. Therefore, it is recommended that early mobilization onset time of patients with ICH should be at least 24 hours after bleeding is stable. The contents of early mobilization include maintaining correct position, assisting patients in passive activities, and guiding patients to active exercise and daily life ability training. The contents and intensity of the activity should be reasonably designed and implemented according to the patient's own situation and desires. Blood pressure and intracranial pressure are important factors influencing early mobilization of patients with ICH. 

Combining the power of industry, government, academia and people, we will jointly build an integrated community support network for preventing disability and delaying dementia to develop a powerful solution module for "smart living" to prevent and delay disability care: a 12-week muscle strengthening exercise program Resistance training, the case will be accompanied by cognitive promotion, life function reconstruction training, social participation elements, and the use of a "healthy passbook" community support network.Disability is basically a diseases state and absolutely falls under clinical framework and Essentially a problem focusing on the Individual as a deviation from the Norm.

 Prostate cancer is the leading cause of cancer among Nigerian men; Prostate Specific Antigen (PSA) is an extremely effective tool for identifying men with prostate cancer. The purpose of this study is to explore the Awareness and Acceptance of PSA (Prostate Specific Antigen) Screening Services among the Middle Age Men Staffers of Achievers University Owo. A descriptive cross sectional study design was used; random sampling technique was used to with the aids of individuals’ staff number to select 138 respondents. Data collection lasted three months using a selfstructured questionnaire with Cronbach Alpha of 0.80 reliability, which was conducted through pilot testing of the instrument. Data collected were analysed using both descriptive and inferential statistics. Respondents’ mean age was 45.36±6.73. 34.8% of the respondents were adjudged having good awareness of Prostate Specific Antigen Screening services while 65.2% did not aware of Prostate Specific Antigen Screening. Majority (65.2%) of the respondents did not accept PSA Screening, it was only 34.8% that accepted the screening procedure as a means of early detection of prostate cancer. The fear of developing prostate cancer made the respondents not accept PSA screening. It was found that P- value 0.1245> 0.05 at 0.05 level of significance, there is no significant relationship between income level and acceptability of PSA (Prostate Specific Antigen) Screening. Also the result revealed there is significant relationship between educational level and acceptability of PSA (Prostate Specific Antigen) Screening with P- value 0.0192 < 0.05 at 0.05

This study included 1456 men and 1411 women who were trauma-exposed and underwent routine health examinations in a community epidemiological investigation. The participants completed the posttraumatic stress disorder (PTSD) Check List-Civilian Version (PCL-C) for PTSD and medical examinations to detect metabolic syndrome. Adjustments for age, marriage, exercise, education, cigarette smoking, cancer, stroke, angina, and thyroid disease were performed. The relationship between PTSD and metabolic syndrome and each of its components was analyzed by multiple logistic regression. In women, PTSD was associated with metabolic syndrome (OR=1.53, 95% CI= 1.01-1.95, p=0.047) and the high-density lipoprotein cholesterol component (OR=1.98, 95% CI= 1.04-2.12, p=0.002). In men, PTSD was related to the hypertension component of metabolic syndrome (OR=0.54, 95% CI= 0.31-0.92, p=0.023). There was also a relationship between PTSD severity and metabolism (OR=1.141, 95% CI= 1.002-1.280, p=0.037) in women, and PTSD was inversely associated with the hypertension component (OR=0.54, 95% CI= 0.31-0.92, p=0.023) in men. PTSD was related to metabolic syndrome only in women. We plan to further research the mechanism of sex differences and dyslipidemia

Recognition and management of deteriorating patients is a matter of serious concern. Deteriorating patients often show signs of physiological deterioration, therefore nurses being in close contact with patients play the frontline caretaker and have greater role in early recognition of ominous events. The objective of the study is to assess the level of Knowledge of nurses in recognizing and managing deteriorating patients in BPKIHS. A descriptive, cross-sectional research design was adopted for this study. Total 70 staff nurses working in Medical, Surgical, Orthopedics, ICU, CCU and Surgical ICU of BPKIHS were selected using population proportionate stratified simple random sampling technique. Self-administered questionnaire was used for data collection and the collected data was analyzed using descriptive and inferential statistics. Among 70 respondents 38.6% of them were from critical care unit and 61.4% from general unit. The mean age of the respondents was 25.86±3.24 SD ranging from 19-34 years old. The overall knowledge level in recognition and management of deteriorating patient was found to be good among 48.6% and poor among 51.4%. Findings revealed that critical care nurses had more knowledge than general unit nurses and was statistically significant (p<0.001). Nurses in overall demonstrated poor knowledge in recognition and management of deteriorating patient. Statistically significant association was found between overall level of knowledge and working area of nurses. Hence there’s need for educational efforts to improve nurses’ knowledge in recognition and management of deteriorating patient.

Cervical cancer is the fourth most frequent cancer in women with an estimated 570,000 new cases in 2018 representing 6.6% of all female cancers. In Nepal, cervical cancer ranks as the 1st most frequent cancer among women age between 15 and 44 years. A comprehensive approach that includes prevention, early diagnosis, effective screening and treatment programmes reduce the high mortality rate from cervical cancer globally. Objective of the study was to identify the knowledge and practice of cervical cancer screening among women attending gynecology OPD.A descriptive cross-sectional study design was used in this study. Hundred and fifty women were selected through purposive sampling technique. A pretested semi structured interview schedule was used to measure research variables. Frequency, percentage, mean and chi-squired test were used to analyze the data.Out of 150 women, mean age was 39.41 ± 10.26 and 78.7% respondents were Hindu. Slightly more than half (52.0%) were heard about cervical cancer screening. Among them, less than half (46.2%) had adequate knowledge and only 8.7% of women had practice of cervical screening. There were no association between knowledge and sociodemographic variables as well as practice and socio-demographic variables. Majority of women have inadequate knowledge and no practice of cervical cancer screening. Therefore cervical cancer screening and awareness program should be emphasized.

Background: Professional identity significantly affects nurses' willingness to practice, which is an important reason for the shortage of nurses. However, Authoritative and effective training program of professional identity remain poorly described. Objective: We performed a literature review to elucidate the influencing factors and educational methods of nursing undergraduate' professional identity. Methods: A literature search was conducted PubMed, Web of Science, Embase, CNKI, the VIP, Wan Fang databases, using the keywords " nursing education" " professional identity". Results: the professional identity of undergraduate nursing students is influenced by various factors, including gender, grade, personality, cognition, reasons for choosing a profession, organizational factors, employment environment, family and social support, etc. Nursing educators enhance professional identity of nursing undergraduates through orientation programs, curriculum innovation and peer support and so on. Conclusions: Nursing educator should consider of characteristics of nursing undergraduates, and attach more importance to professional identity education.

Background and Objective: HPV-related cancers are a significant problem facing the United States, especially considering many of these cancers can be prevented with HPV vaccination. Despite CDC recommendations, HPV vaccination rates continue to remain very low, disproportionately impacting rural communities. The purpose of this quality improvement project was to improve provider recommendation rates to increase HPV vaccination series initiation or subsequent HPV vaccinations in adolescents between the ages of 11 and 17 at two rural healthcare clinics. Methods: 9 providers including 5 MDs, 1 DO, 2 PAs, and 1 NP at two rural healthcare clinics in Atchison, Kansas participated in the project. The project included a 6-week pre-intervention phase to assess provider recommendation rates followed by an educational session with providers and a 6-week intervention phase. The intervention phase consisted of provider recommendation at all visits to reduce the number of missed opportunities, educational handouts on HPV and the HPV vaccine for parents and patients, and a call-back reminder system. Results: Preliminary data reveals a 12.9% increase in provider recommendation rates. The call-back reminder system was responsible for 50 adolescents receiving a dose of the HPV vaccination, 41 of which have now completed the series. Additionally, 6 hepatitis A, 8 meningococcal, and 19 influenza vaccines were also administered to the adolescents returning due to the call-back reminder system. During the 3-month project timeframe, adolescents received a total of 110 HPV vaccinations which is a significant increase from the 42 HPV vaccinations given during the same timeframe the previous year.

-To evaluate the factors affecting readiness for hospital discharge (RHD) and the relationship with chronic disease self efficacy in depression patients. Depression is a disease that requires long-term management, high suicide rate, high recurrence rate, and heavy disease burden. High rate of relapse causes serious mental and economic burden. Evaluation of RHD in terms of patient safety is important. Descriptive and cross-sectional study. The study was carried out with 370 depression patients who were scheduled to be discharged within 2 days in China betweenOctober 2016 -August 2017. The Readinessfor Hospital Discharge Scale (RHDS), Quality of discharge teaching scale (QDTS) and Chronic Disease Self-Efficacy Scale were used

Encyclopedia of Bioanalytical Methods for Bioavailability and Bioequivalence Studies of Pharmaceuticals (E-BABE): It is a unique encyclopedia involving bioanalytical methods for bioavailability and bioequivalence (BA/BE) studies of pharmaceuticals for suitable method selection with thousands of combinations and searches against these methods. Most scrutinized literature was collected from different sources including PubMed. This database has been curetted using published methods for all most all pharmaceuticals. Required information for regular method development/validation such as IUPAC name, structure, solubility, chromatographic conditions, instrumentation information like HPLC, LCMS detection parameters, sample preparations, recovery details, limit of detection and limit of quantification, Tmax, Cmax etc., for routine application in BA/BE studies of pharmaceuticals was incorporated including official pharmacopeias information such as European Pharmacopeia, Japan Pharmacopeia and US Pharmacopeia. Database includes drug based bioanalytical methods covering most required fields and external database links of important drug portals such as drug bank, Rxlist, MEDLINE plus, KEGG Drug ID.

Nurses at all levels must be prepared and developed to lead change to advance health care. Historically, in most healthcare institutes, nursing leadership development programs have focused on nurses in senior management or executive roles rather than those working in front-line leadership roles. This article will describe a professional development initiative program attended by 169 charge nurses. The program has a comprehensive curriculum and road map for developing frontline leadersand ensuring charge nurses are trained, mentored, and supported in their roles. Program development, evaluation, and lessons learned that can be applied in other organizations are discussed

ABSTRACT-Kingdom of Saudi Arabia is facing many health related challenges. It was on 1954 when Ministry of Health (MOH) has established Nursing as a profession. Since the last 64 years, nursing has faced many obstacles, difficulties and challenges and there was a direct impact on the growth and development in Nursing Education. Unfortunately, these challenges facing Nursing Education in Saudi Arabia are increasingly complex and dynamic. The main purpose of this paper is to highlight and discuss those challenges through Structure – Process- Outcome model. Systematic review of the literature published between 1988 till 2018 were reviewed using different electronic database such as Cumulative Index to Nursing and Allied Health Literature (CINAHL), Pro Quest Central, Expanded Academic ASAP, Wiley Interscience (Wiley), MEDLINE (OVID), and SAGE. Databases were accessed using key words: Saudi Arabia, Nursing, Nursing Education, and Challenges. There were 36 studies accessed and discussed these challenges but only 30 studies had studied the direct impact on clinical training and staff education. Challenges facing Nursing Educations in KSA were categorized on Structure- Process Outcome Model. Structural Challenges included shortage of staff and scope of nursing practice, process challenges included role of the Clinical Teachers, educational and teaching methods,

Low to high side category employees can villain. Angry employees has more likely to engage in unethical behaviour at work, a new study has revealed. Researcher has seen poverty during early service. Also, when working in the power politics institute in Pune University researcher observed that trustee take poor employees to bed hungry. To control crime researcher realised that they have to go to ethical college where they will get a mid-day meal.